technologyreview.com: By Emily Singer

Compounds boost endurance and allow mice to run for substantially longer.

The elusive exercise pill just took a step closer to becoming a reality. Scientists have found that two compounds can boost endurance in mice by changing the metabolic properties of the animals’ muscle. One of the drugs appears to mimic some of the benefits of exercise even in sedentary mice. But the most dramatic benefit comes from combining one of the drugs with exercise, enabling mice to run 60 to 75 percent longer. [ read more ]